Growth of immobilized DNA by polymerase: bridging nanoelectrodes with individual dsDNA molecules

Details Growth of immobilized DNA by polymerase: bridging nanoelectrodes with individual dsDNA molecules Growth of immobilized DNA by polymerase: bridging nanoelectrodes with individual dsDNA molecules

2011-02-22

arxiv.org/abs/1102.4594v2

Physics

Biological Physics

5 pages, 3 figures; Nanoscale (2011)

Scientific paper

10.1039/c1nr10518c

We present a method for controlled connection of gold electrodes with dsDNA molecules (locally on a chip) by utilizing polymerase to elongate single-stranded DNA primers attached to the electrodes. Thiol-modified oligonucleotides are directed and immobilized to nanoscale electrodes by means of dielectrophoretic trapping, and extended in a procedure mimicking PCR, finally forming a complete dsDNA molecule bridging the gap between the electrodes. The technique opens up opportunities for building from the bottom-up, for detection and sensing applications, and also for molecular electronics.

Affiliated with

Also associated with

No associations

Rating

Growth of immobilized DNA by polymerase: bridging nanoelectrodes with individual dsDNA molecules does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Growth of immobilized DNA by polymerase: bridging nanoelectrodes with individual dsDNA molecules, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Growth of immobilized DNA by polymerase: bridging nanoelectrodes with individual dsDNA molecules will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-560880