Geometry of proteins: hydrogen bonding, sterics and marginally compact tubes

Biology – Quantitative Biology – Biomolecules

Scientific paper

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12 pages, no figures, revised version accepted for publication in Phisycal Review E

Scientific paper

10.1103/PhysRevE.73.031921

The functionality of proteins is related to their structure in the native state. Protein structures are made up of emergent building blocks of helices and almost planar sheets. A simple coarse-grained geometrical model of a flexible tube barely subject to compaction provides a unified framework for understanding the common character of globular proteins.We argue that a recent critique of the tube idea is not well founded.

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