Force-velocity relations for multiple-molecular-motor transport

Details Force-velocity relations for multiple-molecular-motor transport Force-velocity relations for multiple-molecular-motor transport

2009-06-26

arxiv.org/abs/0906.4861v2

Physical Review E 80, 041923 (2009)

Physics

Biological Physics

5 pages, 3 figures, accepted for publication in Phys. Rev. E

Scientific paper

10.1103/PhysRevE.80.041923

A transition rate model of cargo transport by $N$ molecular motors is proposed. Under the assumption of steady state, the force-velocity curve of multi-motor system can be derived from the force-velocity curve of single motor. Our work shows, in the case of low load, the velocity of multi-motor system can decrease or increase with increasing motor number, which is dependent on the single motor force-velocity curve. And most commonly, the velocity decreases. This gives a possible explanation to some recent

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