Failure to induce Atherosclerosis in `Triton' Hyperlipæmic Guinea Pigs

Physics

Scientific paper

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Scientific paper

IT has been shown that `Triton- WR 1339', a non-ionic surf ace-active agent, induces high hyperlipæmia in rabbits1, rats2, mice3, guinea pigs1,4 and dogs5. Typical atheromasic changes of the aorta, coronary and pulmonary arteries have been demonstrated in `Triton'-treated dogs5. These findings are of some interest, since dogs are usually less susceptible to atherosclerosis, and the atheromasic changes have been obtained in aimals fed with a normal diet.

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