Expression of Treponema pallidum Antigens in Escherichia coli

Details Expression of Treponema pallidum Antigens in Escherichia coli Expression of Treponema pallidum Antigens in Escherichia coli

Apr 1982

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=1982sci...216..522w&link_type=abstract

Science, Volume 216, Issue 4545, pp. 522-523

Physics

Scientific paper

Treponema pallidum DNA was cloned in a bacteriophage. Clones were screened for expression of Treponema pallidum antigens by an in situ radio-immunoassay on nitrocellulose, with the use of subsequent reactions with syphilitic serum and radioiodinated Staphylococcus aureus protein A. One clone, which gave a strong signal, codes for at least seven antigens that react specifically with human antibodies to Treponema pallidum.

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