Erwin Schroedinger, Francis Crick and epigenetic stability

Details Erwin Schroedinger, Francis Crick and epigenetic stability Erwin Schroedinger, Francis Crick and epigenetic stability

2007-04-30

arxiv.org/abs/0704.3957v2

Biol Direct. 2008 Apr 17;3(1):15

Physics

General Physics

New and improved version of the essay, now published in the online journal 'Biology Direct'. Contains more expanded discussion

Scientific paper

Schroedinger's book 'What is Life?' is widely credited for having played a crucial role in development of molecular and cellular biology. My essay revisits the issues raised by this book from the modern perspective of epigenetics and systems biology. I contrast two classes of potential mechanisms of epigenetic stability: 'epigenetic templating' and 'systems biology' approaches, and consider them from the point of view expressed by Schroedinger. I also discuss how quantum entanglement, a nonclassical feature of quantum mechanics, can help to address the 'problem of small numbers' that lead Schroedinger to promote the idea of molecular code-script for explanation of stability of biological order.

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