Enol form of uracil in the GU "wobble" pair. NMR evidence

Physics – Biological Physics

Scientific paper

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2 pages, 3 figures

Scientific paper

GU "wobble" pair may contain either the enol form of uracil and the keto form
of guanine or the enol form of guanine and the keto form of uracil. A direct
proof of uracil existence in enol form can be obtained by using NMR
spectroscopy. In HNN-COSY experiments the GU pair imitates the GC pair due to
the enolization of uracil.

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