Efficient statistical inference for stochastic reaction processes

Physics – Data Analysis – Statistics and Probability

Scientific paper

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4 pages, 2 figures, 2 tables; typos corrected, remark about Kalman smoother added

Scientific paper

10.1103/PhysRevLett.103.230601

We address the problem of estimating unknown model parameters and state variables in stochastic reaction processes when only sparse and noisy measurements are available. Using an asymptotic system size expansion for the backward equation we derive an efficient approximation for this problem. We demonstrate the validity of our approach on model systems and generalize our method to the case when some state variables are not observed.

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