Dynamics of icosahedral viruses: what does Viral Tiling Theory teach us?

Details Dynamics of icosahedral viruses: what does Viral Tiling Theory teach us? Dynamics of icosahedral viruses: what does Viral Tiling Theory teach us?

2008-02-19

arxiv.org/abs/0802.2620v1

Computational and Mathematical Methods in Medicine, 9(03-04), 2008, 211 - 220.

Biology

Quantitative Biology

Biomolecules

10 pages, contribution to the proceedings of the `Second Mathematical Virology Workshop', Edinburgh (6-10 August 2007)

Scientific paper

10.1080/17486700802168270

We present a top-down approach to the study of the dynamics of icosahedral virus capsids, in which each protein is approximated by a point mass. Although this represents a rather crude coarse-graining, we argue that it highlights several generic features of vibrational spectra which have been overlooked so far. We furthermore discuss the consequences of approximate inversion symmetry as well as the role played by Viral Tiling Theory in the study of virus capsid vibrations.

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