Dynamics and coding of a biologically-motivated network

Details Dynamics and coding of a biologically-motivated network Dynamics and coding of a biologically-motivated network

2004-07-23

arxiv.org/abs/q-bio/0407031v1

Int. Journal of Bifurcation and Chaos 16 (2006) 383-394

Biology

Quantitative Biology

Molecular Networks

20 pages Latex, 12 figures

Scientific paper

A four-node network consisting of a negative loop controlling a positive one is studied. It models some of the features of the p53 gene network. Using piecewise linear dynamics with thresholds, the allowed dynamical classes are fully characterized and coded. The biologically relevant situations are identified and conclusions drawn concerning the effectiveness of the p53 network as a tumour inhibitor mechanism.

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