Physics – Biological Physics
Scientific paper
2005-08-25
Physical Review E 72 (2005) 051902
Physics
Biological Physics
Scientific paper
10.1103/PhysRevE.72.051902
We present a nonlinear dynamical model for DNA thermal denaturation, which is based on the finite stacking enthalpies used in thermodynamical nearest-neighbour calculations. Within this model, the finiteness of stacking enthalpies is shown to be responsible for the sharpness of calculated melting curves. Transfer-integral and molecular dynamics calculations are performed to demonstrate that the proposed model leads to good agreement with known experimental results for both homogeneous and inhomogeneous DNA.
Buyukdagli Sahin
Joyeux Marc
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