Dynamic detection of a single bacterium: nonlinear rotation rate shifts of driven magnetic microsphere stages

Details Dynamic detection of a single bacterium: nonlinear rotation rate shifts of driven magnetic microsphere stages Dynamic detection of a single bacterium: nonlinear rotation rate shifts of driven magnetic microsphere stages

2006-10-19

arxiv.org/abs/physics/0610144v1

Physics

Biological Physics

3 pages, 2 figures

Scientific paper

We report on a new technique which was used to detect single Escherichia coli that is based on the changes in the nonlinear rotation of a magnetic microsphere driven by an external magnetic field. The presence of one Escherichia Coli bacterium on the surface of a 2.0 micron magnetic microsphere caused an easily measurable change in the drag of the system and, therefore, in the nonlinear rotation rate. The straight-forward measurement uses standard microscopy techniques and the observed average shift in the nonlinear rotation rate changed by a factor of ~3.8.

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