Physics – Medical Physics
Scientific paper
2003-03-12
Physics
Medical Physics
Scientific paper
A general model for the ontogenetic growth of living organisms has been recently proposed. Here we investigate the extension of this model to the growth of solid malignant tumors. A variety of in vitro and in vivo data are analyzed and compared with the prediction of a 'universal' law, relating properly rescaled tumor masses and tumor growth times. The results support the notion that tumor growth follows such a universal law. Several important implications of this finding are discussed, including its relevance for tumor metastasis and recurrence, cell turnover rates, angiogenesis and invasion.
Degiorgis Piero Giorgio
Deisboeck Thomas S.
Delsanto Pier Paolo
Gabriele Pietro
Guiot Caterina
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