Biology
Scientific paper
Aug 2008
adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=2008spie.7097e..20h&link_type=abstract
Instruments, Methods, and Missions for Astrobiology XI. Edited by Hoover, Richard B.; Levin, Gilbert V.; Rozanov, Alexei Y.; Da
Biology
Scientific paper
We have characterized function related DNA sequences of various organisms using informatics techniques, including fractal dimension calculation, nucleotide and multi-nucleotide statistics, and sequence fluctuation analysis. Our analysis shows trends which differentiate extremophile from non-extremophile organisms, which could be reproduced in extraterrestrial life. Among the systems studied are radiation repair genes, genes involved in thermal shocks, and genes involved in drug resistance. We also evaluate sequence level changes that have occurred during short term evolution (several thousand generations) under extreme conditions.
Cheung Edmond
Cheung Teddy
Flamholz Alex
Holden Todd
Lieberman D.
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