Biology – Quantitative Biology – Molecular Networks
Scientific paper
2008-03-10
Biology
Quantitative Biology
Molecular Networks
24 pages, 8 figures, submitted to Biophysical Journal
Scientific paper
The analysis of complex reaction networks is of great importance in several chemical and biochemical fields (interstellar chemistry, prebiotic chemistry, reaction mechanism, etc). In this article, we propose to simultaneously refine and extend for general chemical reaction systems the formalism initially introduced for the description of metabolic networks. The classical approaches through the computation of the right null space leads to the decomposition of the network into complex ``cycles'' of reactions concerned with all metabolites. We show how, departing from the left null space computation, the flux analysis can be decoupled into linear fluxes and single loops, allowing a more refine qualitative analysis as a function of the antagonisms and connections among these local fluxes. This analysis is made possible by the decomposition of the molecules into elementary subunits, called "reactons" and the consequent decomposition of the whole network into simple first order unary partial reactions related with simple transfers of reactons from one molecule to another. This article explains and justifies the algorithmic steps leading to the total decomposition of the reaction network into its constitutive elementary subpart.
Bersini Hugues
Brandenburg Axel
Plasson Raphael
No associations
LandOfFree
Decomposition of Complex Reaction Networks into Reactons does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.
If you have personal experience with Decomposition of Complex Reaction Networks into Reactons, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Decomposition of Complex Reaction Networks into Reactons will most certainly appreciate the feedback.
Profile ID: LFWR-SCP-O-378941