Culture system for bone metabolic studies

Details Culture system for bone metabolic studies Culture system for bone metabolic studies

Oct 2005

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=2005esasp1290..306v&link_type=abstract

In: Microgravity applications programme: Successful teaming of science and industry. Edited by Andrew Wilson, coordination: Benn

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Life Sciences, Bone Structure

Scientific paper

Understanding the mechanisms governing bone remodelling is essential for a clear understanding of not only pathological conditions such as osteoporosis, but also microgravity-induced bone loss. The scope of this MAP project is the further development (including technical development and biological validation) of an ex vivo culture system for trabecular bone explants, which can be submitted to controlled mechanical stimuli. This should allow the evaluation of the causal relationship between biochemical and mechanical parameters and bone remodelling.

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