Correlations in the T Cell Response to Altered Peptide Ligands

Details Correlations in the T Cell Response to Altered Peptide Ligands Correlations in the T Cell Response to Altered Peptide Ligands

2004-04-20

arxiv.org/abs/q-bio/0404023v1

Biology

Quantitative Biology

Biomolecules

21 pages; 6 figures; to appear in Physica A

Scientific paper

10.1016/j.physa.2004.04.127

The vertebrate immune system is a wonder of modern evolution. Occasionally, however, correlations within the immune system lead to inappropriate recruitment of preexisting T cells against novel viral diseases. We present a random energy theory for the correlations in the naive and memory T cell immune responses. The non-linear susceptibility of the random energy model to structural changes captures the correlations in the immune response to mutated antigens. We show how the sequence-level diversity of the T cell repertoire drives the dynamics of the immune response against mutated viral antigens.

Affiliated with

Also associated with

No associations

Rating

Correlations in the T Cell Response to Altered Peptide Ligands does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Correlations in the T Cell Response to Altered Peptide Ligands, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Correlations in the T Cell Response to Altered Peptide Ligands will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-55941