Cooperativity, sensitivity and noise in biochemical signaling

Details Cooperativity, sensitivity and noise in biochemical signaling Cooperativity, sensitivity and noise in biochemical signaling

2005-12-31

arxiv.org/abs/q-bio/0601001v1

Biology

Quantitative Biology

Molecular Networks

Scientific paper

Cooperative interactions among the binding of multiple signaling molecules is a common mechanism for enhancing the sensitivity of biological signaling systems. It is widely assumed that this increase in sensitivity of the mean response implies the ability to detect smaller signals. We show that, quite generally, there is a component of the noise in such systems that can be traced to the random arrival of the signaling molecules at their receptor sites, and this diffusive noise is not reduced by cooperativity. Cooperativity makes it easier for real systems to reach this physical limit, but cannot reduce the limit itself.

Affiliated with

Also associated with

No associations

Rating

Cooperativity, sensitivity and noise in biochemical signaling does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Cooperativity, sensitivity and noise in biochemical signaling, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cooperativity, sensitivity and noise in biochemical signaling will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-284310