Physics – Biological Physics
Scientific paper
2009-05-19
EPL 86 (2009) 40008
Physics
Biological Physics
6 two-column pages, 5 figures; accepted for publication in Europhysics Letters
Scientific paper
10.1209/0295-5075/86/40008
We investigate the regularity of spontaneous spiking activity on Newman-Watts small-world networks consisting of biophysically realistic Hodgkin-Huxley neurons with a tunable intensity of intrinsic noise and fraction of blocked voltage-gated sodium and potassium ion channels embedded in neuronal membranes. We show that there exists an optimal fraction of shortcut links between physically distant neurons, as well as an optimal intensity of intrinsic noise, which warrant an optimally ordered spontaneous spiking activity. This doubly coherence resonance-like phenomenon depends significantly, and can be controlled via the fraction of closed sodium and potassium ion channels, whereby the impacts can be understood via the analysis of the firing rate function as well as the deterministic system dynamics. Potential biological implications of our findings for information propagation across neural networks are also discussed.
Ozer Mahmut
Perc Matjaz
Uzuntarla Muhammet
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