Compound-specific isotope analysis

Details Compound-specific isotope analysis Compound-specific isotope analysis

2007-09-26

arxiv.org/abs/0709.4164v1

Rapid Communications in Mass Spectrometry 14 (2000) 1337 - 1344

Biology

Quantitative Biology

Biomolecules

Scientific paper

10.1002/1097-0231(20000815)14:15

The isotopic composition, for example, 14C/12C, 13C/12C, 2H/1H, 15N/14N and 18O/16O, of the elements of matter is heterogeneous. It is ruled by physical, chemical and biological mechanisms. Isotopes can be employed to follow the fate of mineral and organic compounds during biogeochemical transformations. The determination of the isotopic composition of organic substances occurring at trace level in very complex mixtures such as sediments, soils and blood, has been made possible during the last 20 years due to the rapid development of molecular level isotopic techniques. After a brief glance at pioneering studies revealing isotopic breakthroughs at the molecular and intramolecular levels, this paper reviews selected applications of compound-specific isotope analysis in various scientific fields.

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