Collecting single molecules with conventional optical tweezers

Details Collecting single molecules with conventional optical tweezers Collecting single molecules with conventional optical tweezers

2007-02-06

arxiv.org/abs/physics/0702044v1

Physical Review E 75(1), 011916 (2007)

Physics

Optics

5 pages, 4 figures

Scientific paper

10.1103/PhysRevE.75.011916

The size of particles which can be trapped in optical tweezers ranges from tens of nanometres to tens of micrometres. This size regime also includes large single molecules. Here we present experiments demonstrating that optical tweezers can be used to collect polyethylene oxide (PEO) molecules suspended in water. The molecules that accumulate in the focal volume do not aggregate and therefore represent a region of increased molecule concentration, which can be controlled by the trapping potential. We also present a model which relates the change in concentration to the trapping potential. Since many protein molecules have molecular weights for which this method is applicable the effect may be useful in assisting nucleation of protein crystals.

Affiliated with

Also associated with

No associations

Rating

Collecting single molecules with conventional optical tweezers does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Collecting single molecules with conventional optical tweezers, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Collecting single molecules with conventional optical tweezers will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-427474