Coding Rules for Amino Acids in the Genetic Code: The Genetic Code is a Minimal Code of Mutational Deterioration

Details Coding Rules for Amino Acids in the Genetic Code: The Genetic Code is a Minimal Code of Mutational Deterioration Coding Rules for Amino Acids in the Genetic Code: The Genetic Code is a Minimal Code of Mutational Deterioration

Feb 2002

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=2002oleb...32...23l&link_type=abstract

Origins of Life and Evolution of the Biosphere, v. 32, Issue 1, p. 23-33 (2002).

Physics

1

Amino Acid Distance, Coding Rule, Globalmutational Deterioration, Standard Genetic Code, Optimization Under Constraints, Single Base Mutation

Scientific paper

Coding rules for amino acids in the genetic code are discussed from the point that the genetic code is a minimal code of mutational deterioration. The global mutational deterioration (GMD) function is defined through several parameters describing single base mutations and amino acid distances. The problem of searching for the global minimum of the GMD function is discussed in some detail. From GMD minimization under initial constraints we have succeeded in deducing the standard genetic code.

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