Biological Circuits: Analysis of a Biological Oscillator

Biology – Quantitative Biology – Molecular Networks

Scientific paper

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Scientific paper

The simple circadian oscillator found in cyanobacteria can be reconstituted in vitro using three proteins-KaiA, KaiB and KaiC. The total phosphorylation level of KaiC oscillates with a circadian period. Recent experiments elucidated the structure and function of the cyanobacterial circadian oscillator, which is driven by sunlight intensity variation and therefore by Earth's rotation. In this paper, we derive the oscillator's equation of motion directly from experimental data, couple it with Earth's rotation and compute its natural periods and resonance curve. Finally, we propose the use of a quantum circuit that is capable of describing the function of the oscillator.

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