Biochemical Model for the Biological Methylation of Mercury suggested from Methylation Studies in vivo with Neurospora crassa

Details Biochemical Model for the Biological Methylation of Mercury suggested from Methylation Studies in vivo with Neurospora crassa Biochemical Model for the Biological Methylation of Mercury suggested from Methylation Studies in vivo with Neurospora crassa

Apr 1971

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=1971natur.230..452l&link_type=abstract

Nature, Volume 230, Issue 5294, pp. 452-454 (1971).

Physics

4

Scientific paper

SINCE the discovery of methyl mercury formation in lake sediments contaminated with inorganic or phenyl mercury1, there has been a good deal of speculation about the mechanism of this synthesis. One process involving methyl-cobalamin (a B12-derivative) was demonstrated in cell-free extracts of methanogenic bacteria2. Vitamin B12 is not known to be involved in the metabolism of Neurospora3,4, and so we have investigated the biosynthesis of methyl mercury in this organism, where the pathway should be different.

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