Physics – Medical Physics
Scientific paper
Jan 1998
adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=1998aipc..420..703a&link_type=abstract
Space technology and applications international forum - 1998. AIP Conference Proceedings, Volume 420, pp. 703-710 (1998).
Physics
Medical Physics
Growth In Microgravity Environments, Aerospace Bio- And Medical Physics
Scientific paper
Crystallizing a macromolecule remains a trial-and-error process that often requires long periods of time and a large supply of sample. Our goal is to develop a new methodology for the crystallization of a macromolecule where the salts and precipitants will be delivered into the macromolecule solution in a controlled and reproducible fashion. In parallel to the basic research, the results will be used to design and test a prototype flight system for shuttle and Space Station usage. The methodology and the hardware system are expected to allow a better understanding of macromolecular crystallization processes as well as to provide a more rapid rational approach to the crystallization of macromolecules. The proposed hardware will be useful in microgravity crystallization experiments where a remote initiation, monitoring, and control of the crystallization process will be provided. In Phase 1, the flight system was developed and used to crystallize proteins. Phase 2 focuses on completing the system development and preparing for the commercialization aspects of this new technology. In this paper the highlights of our NASA Small Business Innovative Research program will be presented. Also what we refer to as Phase 0-why and how we entered into this particular endeavor-will be discussed.
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