Algorithm and performance of a clinical IMRT beam-angle optimization system

Details Algorithm and performance of a clinical IMRT beam-angle optimization system Algorithm and performance of a clinical IMRT beam-angle optimization system

2003-12-16

arxiv.org/abs/physics/0312097v1

Phys. Med. Biol. 48 (2003) 3191-3212

Physics

Medical Physics

Final version that appeared in Phys. Med. Biol. 48 (2003) 3191-3212. Original EPS figures have been converted to PNG files due

Scientific paper

10.1088/0031-9155/48/19/007

This paper describes the algorithm and examines the performance of an IMRT beam-angle optimization (BAO) system. In this algorithm successive sets of beam angles are selected from a set of predefined directions using a fast simulated annealing (FSA) algorithm. An IMRT beam-profile optimization is performed on each generated set of beams. The IMRT optimization is accelerated by using a fast dose calculation method that utilizes a precomputed dose kernel. A compact kernel is constructed for each of the predefined beams prior to starting the FSA algorithm. The IMRT optimizations during the BAO are then performed using these kernels in a fast dose calculation engine. This technique allows the IMRT optimization to be performed more than two orders of magnitude faster than a similar optimization that uses a convolution dose calculation engine.

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