Biology – Quantitative Biology – Neurons and Cognition
Scientific paper
2005-01-12
Biology
Quantitative Biology
Neurons and Cognition
12 pages, 9 figures and 1 table
Scientific paper
This article describes the investigation of morphological variations among two set of neuronal cells, namely a control group of wild type rat cells and a group of cells of a trangenic line. Special attention is given to sigular points in the neuronal structure, namely the branching points and extremities of the dendritic processes. The characterization of the spatial distribution of such points is obtained by using a recently reported morphological technique based on forced percolation and window-size compensation, which is particularly suited to the analysis of scattered points presenting several coexisting densities. Different dispersions were identified in our statistical analysis, suggesting that the transgenic line of neurons is characterized by a more pronounced morphological variation. A classification scheme based on a canonical discriminant function was also considered in order to identify the morphological differences.
Alpar Alan
Arendt Thomas
Barbosa Marconi Soares
Fontoura Costa Luciano da
Gartner Ulrich
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