Accurate Quantification of Fractional Blood Volume in Lung Tissue.

Details Accurate Quantification of Fractional Blood Volume in Lung Tissue. Accurate Quantification of Fractional Blood Volume in Lung Tissue.

May 2002

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=2002ismr.proc.1983t&link_type=abstract

Proceedings of the Tenth Scientific Meeting of the International Society for Magnetic Resonance in Medicine, Honolulu, HI, 2002,

Physics

Scientific paper

We have implemented a method for measuring fractional blood volume in tissue, and for the first time have quantitatively verified the technique in a dialysis canister "phantom", and applied it in lung tissue. The known geometrical parameters and specifications of the dialysis canister allow an extremely accurate determination of the "intravascular" volume, a measurement that was matched extremely well by the MR method. We then used the method to successfully determine microvascular blood volume in an unfixed excised rabbit lung, and found good agreement with previously measured values obtained by microscopic examination of fixed specimens.

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