A Preliminary Work on Evolutionary Identification of Protein Variants and New Proteins on Grids

Details A Preliminary Work on Evolutionary Identification of Protein Variants and New Proteins on Grids A Preliminary Work on Evolutionary Identification of Protein Variants and New Proteins on Grids

2008-04-08

arxiv.org/abs/0804.1202v1

Dans AINA 2006, HIPCOMB Workshop (2006)

Biology

Quantitative Biology

Biomolecules

Scientific paper

Protein identification is one of the major task of Proteomics researchers. Protein identification could be resumed by searching the best match between an experimental mass spectrum and proteins from a database. Nevertheless this approach can not be used to identify new proteins or protein variants. In this paper an evolutionary approach is proposed to discover new proteins or protein variants thanks a "de novo sequencing" method. This approach has been experimented on a specific grid called Grid5000 with simulated spectra and also real spectra.

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