A New Form-Factor Method for the Analysis of Tissue Fluorescence

Details A New Form-Factor Method for the Analysis of Tissue Fluorescence A New Form-Factor Method for the Analysis of Tissue Fluorescence

2005-10-20

arxiv.org/abs/q-bio/0510041v1

Biology

Quantitative Biology

Biomolecules

13 pages, 7 figures, submitted to "Journal of Medical Physics", 2005. As the supplemental material, 4 animation files illustra

Scientific paper

The aim of this article is to present a developed method that decomposes the autofluorescence spectrum into the spectra of naturally occurring biochemical components of biotissue. It requires knowledge of detailed spectrum behaviour of different endogenous fluorophores. We have studied the main bio-markers in human tissue and proposed a simple modelling algorithm for their spectra shapes. The empirical method was tested theoretically by quantum-mechanical calculations of the spectra in the unharmonic Morse potential approach.

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