A multi-scale approach to the physics of ion beam cancer therapy

Details A multi-scale approach to the physics of ion beam cancer therapy A multi-scale approach to the physics of ion beam cancer therapy

2008-07-16

arxiv.org/abs/0807.2597v1

Physics

Biological Physics

submitted to RADAM2008 proceedings. 8 pages,5 Figures, class files for AIP included

Scientific paper

10.1063/1.3058987

We propose a multi-scale approach to understanding physics related to the ion/proton-beam cancer therapy and calculation of the probability of the DNA damage as a result of irradiation of patients with energetic (up to 430 MeV/u) ions. This approach is inclusive with respect to different scales starting from the long scale defined by the ion stopping followed by a smaller scale defined by secondary electrons and radicals ending with the shortest scale defined by interactions of secondaries with the DNA. We present calculations of the probabilities of single and double strand breaks of the DNA and suggest a way of further elaboration of such calculations.

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