A twist in chiral interaction between biological helices

Physics – Biological Physics

Scientific paper

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7 pages, 2 figures, PDF file only

Scientific paper

10.1103/PhysRevLett.84.2537

Using an exact solution for the pair interaction potential, we show that long, rigid, chiral molecules with helical surface charge patterns have a preferential interaxial angle ~((RH)^1/2)/L, where L is the length of the molecules, R is the closest distance between their axes, and H is the helical pitch. Estimates based on this formula suggest a solution for the puzzle of small interaxial angles in a-helix bundles and in cholesteric phases of DNA.

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