Optimal evaluation of single-molecule force spectroscopy experiments

Details Optimal evaluation of single-molecule force spectroscopy experiments Optimal evaluation of single-molecule force spectroscopy experiments

2007-11-08

arxiv.org/abs/0711.1245v1

Physics

Biological Physics

4 pages, 3 figures, accepted for publication in Phys. Rev. E

Scientific paper

10.1103/PhysRevE.76.052901

The forced rupture of single chemical bonds under external load is addressed. A general framework is put forward to optimally utilize the experimentally observed rupture force data for estimating the parameters of a theoretical model. As an application we explore to what extent a distinction between several recently proposed models is feasible on the basis of realistic experimental data sets.

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