A model for the prebiotic synthesis of peptides which throws light on the origin of the genetic code and the observed chirality of life

Physics

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Scientific paper

A model is proposed which indicates that peptides could have been synthesized on RNA templates. L-amino acids are selectively trapped and orientated in clefts in an apparently stable RNA structure attached to a solid phase. Each cleft is bounded by three bases which correspond to the codon for that amino acid. Rotation during a dehydration phase orientates the amino acids so that peptide bond formation can occur by condensation. Rehydration releases the formed peptides.

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