Physics
Scientific paper
Jun 1980
adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=1980natur.285..550s&link_type=abstract
Nature, Volume 285, Issue 5766, pp. 550-554 (1980).
Physics
13
Scientific paper
The nucleotide sequences of the terminal regions of an infectious integrated retrovirus cloned in the modified λ phage cloning vector Charon 4A have been elucidated. There is a 569-base pair direct repeat at both ends of the viral DNA. The cell-virus junctions at each end consist of a 5-base pair direct repeat of cell DNA next to a 3-base pair inverted repeat of viral DNA. This structure resembles that of a transposable element and is consistent with the protovirus hypothesis that retroviruses evolved from the cell genome.
Mizutani Satoshi
Shimotohno Kunitada
Temin Howard M.
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