Physics – Medical Physics
Scientific paper
Jul 2004
adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=2004apsp.conf..431s&link_type=abstract
ASTROPARTICLE, PARTICLE AND SPACE PHYSICS, DETECTORS AND MEDICAL PHYSICS APPLICATIONS. Proceedings of the 8th Conference. Held 6
Physics
Medical Physics
Scientific paper
The combination of new detector technologies and rapidly increasing computing power is contributing to major developments in positron emission tomography (PET) imaging. The uniqueness of PET resides in its ability to detect very small concentrations of radioactively labeled tracers specifically designed to investigate selected biological functions. The desire to quantitatively observe increasingly complex biological processes together with the need of furthering research in small animal models of disease are pushing the limits of imaging spatial resolution and sensitivity. Resolution of approximately 10 mm3 is now achievable in human size brain scanners, while 1 mm3 can almost be reached in small animal imaging. Such ability will enable a more detailed exploration of healthy and disease function with the ultimate goal of imaging at a molecular level and of detecting pre-clinical disease induced changes.
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