Physics
Scientific paper
Dec 2007
adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=2007oleb...37..537f&link_type=abstract
Origins of Life and Evolution of Biospheres, Volume 37, Issue 6, pp.537-553
Physics
4
Protocell, Origin Of Life, Prebiotic Chemistry, Prebiotic Environments
Scientific paper
The paper deals with molecular self-organization leading to formation of a protocell. Plausible steps towards a protocell include: polymerization of peptides and oligonucleotides on mineral surfaces; coevolution of peptides and oligonucleotides with formation of collectively autocatalytic sets; self-organization of short peptides into vesicles; entrapment of the peptide/oligonucleotide systems in mixed peptide and simple amphiphile membranes; and formation of functioning protocells with metabolism and cell division. The established propensity of short peptides to self-ordering and to formation of vesicles makes this sequence plausible. We further suggest that evolution of a protocell produced cellular ancestors of viruses as well as ancestors of cellular organisms.
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