Mathematics – Probability
Scientific paper
2002-12-02
Statistical Applications in Genetics and Molecular Biology 3 (1) 8, http://www.bepress.com/sagmb/vol3/iss1/art8 (2004)
Mathematics
Probability
The revision of 3/29/04 has a new subtitle to reflect the changed emphasis
Scientific paper
Given a multiple testing situation, the null hypotheses that appear to have sufficiently low probabilities of truth may be rejected using a simple, nonparametric method of decision theory. This applies not only to posterior levels of belief, but also to conditional probabilities in the sense of relative frequencies, as seen from their equality to local false discovery rates (dFDRs). This approach neither requires the estimation of probability densities, nor of their ratios. Decision theory can inform the selection of false discovery rate weights. Decision theory is applied to gene expression microarrays with discussion of the applicability of the assumption of weak dependence.
No associations
LandOfFree
Error-rate and decision-theoretic methods of multiple testing: Which genes have high objective probabilities of differential expression? does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.
If you have personal experience with Error-rate and decision-theoretic methods of multiple testing: Which genes have high objective probabilities of differential expression?, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Error-rate and decision-theoretic methods of multiple testing: Which genes have high objective probabilities of differential expression? will most certainly appreciate the feedback.
Profile ID: LFWR-SCP-O-602647