Evolution models with base substitutions, insertions, deletions and selection

Details Evolution models with base substitutions, insertions, deletions and selection Evolution models with base substitutions, insertions, deletions and selection

2009-08-12

arxiv.org/abs/0908.1617v1

PHYSICAL REVIEW E 78, 061920(2008)

Biology

Quantitative Biology

Populations and Evolution

6 pages, 2 figures

Scientific paper

The evolution model with parallel mutation-selection scheme is solved for the case when selection is accompanied by base substitutions, insertions, and deletions. The fitness is assumed to be either a single-peak function (i.e., having one finite discontinuity) or a smooth function of the Hamming distance from the reference sequence. The mean fitness is exactly calculated in large-genome limit. In the case of insertions and deletions the evolution characteristics depend on the choice of reference sequence.

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