Sequential nonparametrics and semiparametrics: Theory, implementation and applications to clinical trials

Mathematics – Statistics Theory

Scientific paper

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Published in at http://dx.doi.org/10.1214/193940307000000257 the IMS Collections (http://www.imstat.org/publications/imscollec

Scientific paper

10.1214/193940307000000257

One of Pranab K. Sen's major research areas is sequential nonparametrics and semiparametrics and their applications to clinical trials, to which he has made many important contributions. Herein we review a number of these contributions and related developments. We also describe some recent work on nonparametric and semiparametric inference and the associated computational methods in time-sequential clinical trials with survival endpoints.

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