Standard Bicarbonate Values of Whole Blood

Details Standard Bicarbonate Values of Whole Blood Standard Bicarbonate Values of Whole Blood

May 1962

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=1962natur.194..480p&link_type=abstract

Nature, Volume 194, Issue 4827, pp. 480 (1962).

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Scientific paper

THE convenience of the interpolation techniques1,2 for the assessment of acid-base imbalance in patients has been widely recognized, and in clinical surgery the ability to differentiate rapidly between the metabolic and respiratory components of such a disturbance has special value. In particular, the standard bicarbonate value, defined as the bicarbonate content of oxygenated blood at 38° C. equilibrated at a PCO2 of 40 mm. mercury provides a quantitative assessment of metabolic disorder. It was therefore disconcerting that when 63 arterial blood samples from a group of 22 patients anæsthetized with halothane were analysed, the standard bicarbonate values obtained (18.14 +/- 1.94 m.equiv.) were significantly lower than those quoted by Astrup et al.3 (22.9 +/- 1.5 m.equiv.). Because there was no other evidence of metabolic acidosis in these patients and because the bicarbonate value of plasma (23.28 +/- 2.82 m.equiv.) in a similar group under the same conditions fell within the range of Astrup's figures it was decided to establish our own standards.

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