Computer Science
Scientific paper
Oct 2004
adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=2004spie.5578..202r&link_type=abstract
Photonics North 2004: Optical Components and Devices. Edited by Armitage, John C.; Fafard, Simon; Lessard, Roger A.; Lampropoul
Computer Science
Scientific paper
An optical system injecting light directly to the skin and collecting the backscattered portion of the light that has been spectrally modified within the skin has been designed and fabricated. This method reduces the noise generated by the specular component practically to zero. The initial device involved a single channel, optical-fibre-based illuminator and collector connected with a spectroscope. The single channel probing head scanned the skin using a mechanical shifting device. Seven clinical tests performed on patients with suspect skin lesions have been tested with our device, and later biopsy was taken as a "gold standard" procedure. Three cases proved to be melanoma and our spectra indicated differences from those collected from non-melanoma lesions. The process of collecting spectral data was time consuming (about 30 min) and thus not acceptable for a medical procedure. To accelerate the process of data collection from the skin, using the same principle of diffuse spectroscopy, an imaging device was conceived which is able to collect the skin spectral response at once from a relatively sizeable skin area. The requirement of negligible specular component was considered of paramount importance. Two possible approaches are feasible to satisfy this requirement: 1. Collection of backscattered light directly from the skin 2. Injection of illuminating light directly to the skin without creating reflections directly from skin. We decided to use the second approach and construct a circular, circumferential illuminator with angled light injection. Before fabricating this illuminator, a thorough analysis was performed to optimize its radius and angle of injection in order to receive the highest uniformity of diffuse light in the skin. Monte-Carlo simulation was applied to a three layer skin approximation. Only three layers were considered due to the assumption that the device must be able to diagnose early melanoma before reaching metastasis. The results of the simulation are presented.
Melnyk Ivan
Oldham Bradley
Rawicz Andrew H.
No associations
LandOfFree
Optimization of illumination for a diffuse-spectroscopy-based early melanoma diagnostic imager does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.
If you have personal experience with Optimization of illumination for a diffuse-spectroscopy-based early melanoma diagnostic imager, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Optimization of illumination for a diffuse-spectroscopy-based early melanoma diagnostic imager will most certainly appreciate the feedback.
Profile ID: LFWR-SCP-O-1473298