Nonenzymatic phosphorylation of acetate by carbamyl phosphate

Computer Science

Scientific paper

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Scientific paper

It is found that carbamyl phosphate is an efficient condensing agent for acetate and hydroxylamine in the presence of Be2+ and Al3+. The reaction has an optimum at pH 4 and is completed within 30 min. The yield of hydroxamate formation reaches 30% (based on initial carbamyl phosphate). Acetylphosphate as the intermediary product of this reaction was identified by P-NMR spectroscopy.

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