FTIR spectroscopy as an analytical tool for solid phase synthesis

Details FTIR spectroscopy as an analytical tool for solid phase synthesis FTIR spectroscopy as an analytical tool for solid phase synthesis

Jun 1998

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=1998aipc..430..509c&link_type=abstract

The eleventh international conference on fourier transform spectroscopy. AIP Conference Proceedings, Volume 430, pp. 509-512 (1

Computer Science

Organic Compounds, Polymers

Scientific paper

Methods for obtaining spectra of organic compounds bound to polymer supports for solid-phase synthesis are compared. ATR is the most convenient method for compounds on beads while diffuse reflection with abrasive sampling is preferred for crown supports. Microscopy is used for single beads or to investigate the distribution on crowns. FT Raman spectra can be obtained very easily but the data are perhaps less useful than IR for monitoring reactions.

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