Cellular track model of biological damage to mammalian cell cultures from galactic cosmic rays

Mathematics – Logic

Scientific paper

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Biological Models (Mathematics), Cells (Biology), Damage Assessment, Galactic Cosmic Rays, Heavy Ions, Radiation Damage, Radiation Protection, Relative Biological Effectiveness (Rbe), Biological Effects, Mammals, Radiobiology, Scaling Laws, Solar Activity Effects, Space Missions, Spacecraft Shielding

Scientific paper

The assessment of biological damage from the galactic cosmic rays (GCR) is a current interest for exploratory class space missions where the highly ionizing, high-energy, high-charge ions (HZE) particles are the major concern. The relative biological effectiveness (RBE) values determined by ground-based experiments with HZE particles are well described by a parametric track theory of cell inactivation. Using the track model and a deterministic GCR transport code, the biological damage to mammalian cell cultures is considered for 1 year in free space at solar minimum for typical spacecraft shielding. Included are the effects of projectile and target fragmentation. The RBE values for the GCR spectrum which are fluence-dependent in the track model are found to be more severe than the quality factors identified by the International Commission on Radiological Protection publication 26 and seem to obey a simple scaling law with the duration period in free space.

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