Mapping Phase Boundaries of 3-Component Model Membrane by Monte Carlo Simulation

Details Mapping Phase Boundaries of 3-Component Model Membrane by Monte Carlo Simulation Mapping Phase Boundaries of 3-Component Model Membrane by Monte Carlo Simulation

Apr 2006

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=2006aps..apr.d1046a&link_type=abstract

American Physical Society, APS April Meeting, April 22-26, 2006, abstract #D1.046

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Three-component model membrane constituted of two phospholipids and cholesterol is a useful system to study many cell membrane phenomena, such as lipid raft formation and phase separation. Extracting the molecular interactions from the existing experimental membrane data or to extend further to predict new phenomena poses lot of challenges. The problem demands correct computational methodologies along with relevant thermodynamics of model system. In this work, we will present Monte Carlo simulation results of three-component model membranes. The detailed computational methodologies to simulate phase separations in the ternary system will be presented.

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