Biology – Quantitative Biology – Populations and Evolution
Scientific paper
2008-08-27
Biology
Quantitative Biology
Populations and Evolution
17 pages, 7 figures
Scientific paper
New models for evolutionary processes of mutation accumulation allow hypotheses about the age-specificity of mutational effects to be translated into predictions of heterogeneous population hazard functions. We apply these models to questions in the biodemography of longevity, including proposed explanations of Gompertz hazards and mortality plateaus, and use them to explore the possibility of melding evolutionary and functional models of aging.
Evans Steven N.
Steinsaltz David R.
Wachter Kenneth W.
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