Velocity oscillations in actin-based motility

Details Velocity oscillations in actin-based motility Velocity oscillations in actin-based motility

2007-04-11

arxiv.org/abs/0704.1390v1

Biology

Quantitative Biology

Cell Behavior

5 pages, 6 figures

Scientific paper

We present a simple and generic theoretical description of actin-based motility, where polymerization of filaments maintains propulsion. The dynamics is driven by polymerization kinetics at the filaments' free ends, crosslinking of the actin network, attachment and detachment of filaments to the obstacle interfaces and entropic forces. We show that spontaneous oscillations in the velocity emerge in a broad range of parameter values, and compare our findings with experiments.

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