Ultraweak bioluminescence imaging and image processing

Details Ultraweak bioluminescence imaging and image processing Ultraweak bioluminescence imaging and image processing

Sep 1996

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=1996spie.2894..276c&link_type=abstract

Proc. SPIE Vol. 2894, p. 276-281, Detectors, Focal Plane Arrays, and Applications, William G. Frederick; Junhong Su; Marc Wigdor

Statistics

Applications

Scientific paper

A photon counting imaging system which can detect emission down to the order of 1 counts cm(superscript -2) sec(superscript -1) (at the photocathode) has been developed, and it has been used to obtain the ultraweak bioluminescence images of a living Kunming mouse. In this paper, we give statistical analysis for calculation of the photon distribution in images obtained, and we use Chi-square ((chi) (superscript 2)) statistic to get signal and noise distribution to process these images. It has been proved that the imaging system has the ability in detecting ultraweak bioluminescence of animals, and the statistical method for image processing can effectively increase the signal/noise ratio and improve the image quality.

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