The Triplet Genetic Code had a Doublet Predecessor

Details The Triplet Genetic Code had a Doublet Predecessor The Triplet Genetic Code had a Doublet Predecessor

2004-03-25

arxiv.org/abs/q-bio/0403036v2

Journal of Theoretical Biology 233 (2005) 527-532

Biology

Quantitative Biology

Genomics

10 pages (v2) Expanded to include additional features, including likely relation to the operational code of the tRNA-acceptor

Scientific paper

Information theoretic analysis of genetic languages indicates that the naturally occurring 20 amino acids and the triplet genetic code arose by duplication of 10 amino acids of class-II and a doublet genetic code having codons NNY and anticodons $\overleftarrow{\rm GNN}$. Evidence for this scenario is presented based on the properties of aminoacyl-tRNA synthetases, amino acids and nucleotide bases.

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